Cajaninstilbene acid

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August undefined, 2024

WebMar 8, 2024 · Cajaninstilbene acid (CSA) is a natural stilbene compound isolated from the leaves of pigeon pea [Cajanus cajan (L.) Millsp.]. The pigeon pea is commonly … WebMar 21, 2024 · Isowighteone (3’-isoprenyl genistein) is a prenylated stilbenoid derivative that exhibits neuroprotective, antibacterial, and anti-inflammatory properties. To establish a bioproduction system for this bioactive compound, hairy root cultures of pigeon pea ( Cajanus cajan (L.) Millsp.) were deve …

Anti-Inflammatory Effects of Cajaninstilbene Acid and Its

http://renkang.weikeqi-biotech.com/product/883e907999113.html WebNov 1, 2024 · General synthetic route of cajaninstilbene acid derivatives 3a-3p and 4a-4h. 2. Materials and methods 2.1. Chemistry The Furanone C-30 was chemically synthesized according to the literature [ 32] and was used as a positive control. The compound 1 was synthesized according to the literature [ 33 ]. contributory vs rollover ira

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WebMar 1, 2024 · Cajaninstilbene acid (CSA), a main bioactive constituent in pigeon pea leaves, has been reported to exhibit various pharmacological activities, including antioxidative [23], anti-tumor [24], hypoglycemic [5] and antibacterial [26] effects. WebNational Center for Biotechnology Information contributory winding up

Production and Secretion of Isowighteone in Hairy Root Cultures …

Cocultivation of pigeon pea hairy root cultures and Aspergillus for …

WebNov 15, 2011 · Five fungal endophytes (K4, K5, K6, K9, K14) producing Cajaninstilbene acid (CSA, 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid) were isolated from the roots of pigeon pea [Cajanus cajan ... WebFeb 17, 2024 · Pigeon pea hairy root cultures (PPHRCs) have been proven to be a promising alternative for the production of health-beneficial phenolic compounds, such as the most important health-promoting compound, i.e., cajaninstilbene acid (CSA). contridicting topics in health sciencesWebCajaninstilbene acid protects corticosterone-induced injury in PC12 cells by inhibiting oxidative and endoplasmic reticulum stress-mediated apoptosis. Neurochemistry … fall feast clip art

"WebNov 14, 2024 · The natural product cajaninstilbene acid (CSA, Fig. 1) has an antibacterial scaffold and we have identified several cajaninstilbene acid derivatives with excellent antibacterial activity against ... " - Cajaninstilbene acid

Cajaninstilbene acid

WebAug 1, 2024 · Cajaninstilbene acid and its derivatives ( 13a-13i) were obtained by hydrolysis of 12a-12i. In this way, we accomplished the synthesis of cajaninstilbene acid and its derivatives through a building block in only six steps. The synthesis route is shorter than those previously reported and produces a much higher overall yield [ 11, 13 ]. WebFeb 24, 2024 · Cajaninstilbene acid (CSA), an active stilbene isolated from the leaves of pigeon pea (Cajanus cajan), exhibits several bioactivities.To develop CSA as a potential nutraceutical and provide pharmacokinetic foundations for its further in vivo bioactivity studies, this study aims to explore its absorption, metabolism, and excretion …

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WebJan 12, 2011 · The antioxidant properties, DNA damage protective activities, and xanthine oxidase (XOD) inhibitory effect of cajaninstilbene acid (CSA) derived from pigeon pea leaves were studied in the present work. Compared with resveratrol, CSA showed stronger antioxidant properties, DNA damage protective activity, and XOD inhibition activity. WebThe total yield of eight flavonoids (414.95 ± 50.68 μg/g DW) in 42-day-old PPHRCs exposed to 4 h of UV-B radiation increased by 1.49-fold as against control, whereas the yield of cajaninstilbene acid (6566.01 ± 702.14 μg/g DW) in PPHRCs undergoing 10 h of UV-B radiation significantly increased by 2.31-fold over control.

WebJan 30, 2024 · Finally, we identified the cajaninstilbene acid, a main bioactive stilbene component in MECC, which significantly modulated the LDLR and PCSK9 expression in HepG2 cells. Our current data suggest that the cajaninstilbene acid may contribute to the hypocholesterolemic activity of Cajanus cajan L. leaves. WebThe antioxidant properties, DNA damage protective activities, and xanthine oxidase (XOD) inhibitory effect of cajaninstilbene acid (CSA) derived from pigeon pea leaves were studied in the present work. Compared with resveratrol, CSA showed stronger antioxidant properties, DNA damage protective activity, and XOD inhibition activity. The IC50 values …

WebAug 15, 2010 · Cajanuslactone (1), together with pinostrobin (2) and cajaninstilbene acid (3), was isolated from the bioassay-guided fraction of pigeon pea leaves, using a … WebNov 16, 2024 · In this study, a synthetic approach to the natural products cajaninstilbene acid (1) and amorfrutins A (2) and B (3) has been developed and was characterized by …

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WebMar 8, 2024 · Acetaminophen (APAP)-induced liver injury (AILI) is the main cause of acute liver failure in the developed countries. The present study aimed to evaluate the therapeutic efficacy of cajaninstilbene acid (CSA), a major stilbene compound derived from the leaves of pigeon pea [Cajanus cajan (L.) Millsp.], against AILI.CSA (50, 75 mg/kg, p. o.) was … fall feasts 2022WebJan 16, 2015 · A common building block for the synthesis of amorfrutin and cajaninstilbene acid derivatives has been developed. The library of synthesized compounds has enabled identification of new nontoxic ligands of peroxisome proliferator-activated receptors (PPAR) and potential inhibitors of the transcriptional corepressor protein NCoR. fall feastWebSep 1, 2014 · Background/Aims: Cajaninstilbene acid (3-hydroxy-4-prenyl-5-methoxystilben-2 -carboxylic acid, CSA), a natural stilbene isolated from the leaves of Cajanus cajan, has attracted considerable ... contridictions in the bible hraph