WebCisplatin Cl2H6N2Pt CID 5460033 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. WebFeb 1, 2024 · Cisplatin has been widely used for chemotherapy of head, neck, gastrointestinal, lung, and ovarian cancers. The therapeutic effect of cisplatin is based …
Cisplatin - an overview ScienceDirect Topics
WebOct 1, 2014 · Our data suggested that physicochemical properties of lipid bilayers including the gel to liquid phase transition temperature will influence the rate of drug release, which in turn, enhances the therapeutic activity of encapsulated cisplatin. Phospholipids with higher temperature of transitions (T m) (HSPC and DPPC) better retained entrapped … WebKinetics of the adduct formation of cisplatin and its hydrolysis products with 5′-GMP was investigated using capillary electrophoresis (CE) under ‘simulated physiological conditions’. Therefore, chloride ion and phosphate concentration as well as the pH were chosen comparable to intracellular conditions. grand translation
How Physicochemical Properties of Drugs Affect Their Metabolism and …
WebJan 31, 2024 · Rat NRK-52E and human HK-2 subjected to cisplatin-induced AKI were treated with four polyherbs, Injinhotang (IJ), Ucha-Shinki ... has attracted interest because of the favorable physicochemical properties of these materials, including antibacterial properties and excellent biocompatibility. Multimetallic NPs, particularly those formed by … WebIt is known from the physicochemical properties of molecules that lipophilic molecules pass easily through the airway epithelium via passive transport, ... The respiratory adverse effects recorded were due to the physicochemical properties of the liposomal cisplatin, and grade 2 was not exceeded in any case. Non-specific bronchitis, nausea, and ... WebOct 5, 2014 · Cisplatin has a molecular weight of 301.1 gm/mol, a density of 3.74 g/cm 3, a melting point of 270° C, a log K ow of -2.19 and a water solubility of 2.53 g/L at … chinese school stockton ca