WebDichloromethane causes moderate skin irritation in rabbits and reversible irritation (moderate to severe changes) to the rabbit eye (47, 82). 3.3.3 Skin sensitisation No data … WebThey include: documents justifying selection of the substances, decisions to request more information. Member States' conclusions and Member States' final evaluation reports are included for substances for which evaluation has been finalised. Notes to the Substance Evaluation table Dichloromethane EC / List no: 200-838-9 CAS no: 75-09-2
Substance evaluation - CoRAP - ECHA - Europa
WebDichloromethane is thought to readily transfer across the blood-brain barrier by passive diffusion, as evidenced by the detection of radioactivity in brain tissue 48 hours after exposures of rats to radiolabeled dichloromethane at concentrations of 50, 500, or 1500 ppm for 6 hours. It can be transferred across the placenta, and WebDichloromethane (DCM) or Methylene Chloride (200-838-9; 75-09-2) Chloroform (CFM) or Trichloromethane (200-663-8; 67-66-3) Carbon Tetrachloride or Tetrachloromethane (200-262-8; 56-23-5) Trichloroethylene (TRI) (201-167-4; 79-01-6) Tetrachloroethylene or Perchloroethylene (204-825-9; 127-18-4) grand biscuit cinnamon roll recipe
Evaluation of the carcinogenicity of dichloromethane in rats, …
Webdichloromethane; methylene chloride EC number: 200-838-9 CAS number: 75-09-2 Guidance on Safe Use Administrative data First-aid measures Fire-fighting measures Accidental release measures Handling and storage Transport information Exposure controls / personal protection Stability and reactivity Disposal considerations Administrative data Webdichloromethane; methylene chloride EC number: 200-838-9 CAS number: 75-09-2 Genetic toxicity: in vitro Currently viewing: Administrative data Data source Materials and methods Results and discussion Applicant's summary and conclusion Administrative data Endpoint: in vitro gene mutation study in bacteria Type of information: experimental study WebNov 18, 2011 · Note: ADAF -- EPA has concluded that dichloromethane is carcinogenic by a mutagenic mode of action. Application of age-dependent adjustment factors (ADAFs) … chinchilla hay feeder