WebMay 22, 2024 · In the Drug Rediscovery Protocol (DRUP) , a national ongoing pan-cancer multi-drug basket/umbrella trial, patients are treated off-label with registered drugs based on their tumor molecular profile. The innovative design allows for an infinite number of cohorts, testing multiple hypotheses in parallel. The DRUP facilitates access to potentially ... WebJun 15, 2024 · Therefore, we initiated the Drug Rediscovery Protocol (DRUP), an innovative and adaptive precision oncology trial aimed at identifying signals of activity in …
Drug rediscovery protocol allows doctors to prescribe anticancer drugs ...
WebMethod Article. The Drug Rediscovery Protocol (DRUP trial): A Dutch National Study on behalf of the Center for Personalized Cancer Treatment (CPCT) to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to determine the Potential Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile WebThe Drug Rediscovery Protocol (DRUP trial) is a national Dutch multi-center, multi-drug, pan-cancer basket trial in which patients with an incurable malignancy, who have exhausted standard treatment options, are treated off label with registered targeted therapies and immune checkpoint inhibitors, based on their tumor molecular profile. shooting in south tucson
The Drug Rediscovery Protocol (DRUP Trial) (DRUP)
WebNov 4, 2024 · The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs. Nature 574, 127–131 (2024). Luan Nguyen. PhD student, UMC Utrecht. Follow. Please sign in or register for FREE If you are a registered user on Nature Portfolio Cancer Community, please sign in WebApr 1, 2024 · In the Drug Rediscovery Protocol (DRUP), patients with therapy-refractory metastatic cancers harboring an actionable molecular profile are matched to … WebFeature papers represent the most advanced research with significant potential for high impact in the field. A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. shooting in south st petersburg