WebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in Physiology or Medicine 2024 was awarded for the discovery of HIF. HIF1A is a basic helix-loop-helix PAS domain containing ... WebHIF-1α是HIF-1的调节亚基，是主要的功能亚基，对HIF-1的转录活性起着关键性作用，HIF-1α基因位于人类14号染色体上，基因全长约52.7kb，共有16个外显子，氨基酸数量为826个。. 近期研究表明，该基因与非酒精性脂肪性肝病（NAFLD）密切相关。.
2024诺奖解读：缺氧诱导因子(HIF)的发现及基于其通路 ...
Web唾液腺腺样囊性癌(salivary adenoid cystic carcinoma，SACC)是头颈部唾液腺最常见的恶性肿瘤之一，具有嗜神经生长、远期复发率高及易发生全身远处转移等独特的生物学行为 … Web1 de mai. de 2008 · To understand physiological meaning and condition which regulates VDUP1 and HIF1α, some stimuli were tested for HIF1α regulation. TNF-α is known to increase HIF1α expression under normoxia condition [13], [14].When HIF1α was increased by TNF-α treatment, VDUP1 was reduced simultaneously (Fig. 2 G).Next, VDUP … duni playground
细胞信号通路详解之HIF1α通路_-Alpha - 搜狐
Web缺氧诱导因子1（hif-1）是一种碱性螺旋-环-螺旋-pas结构域转录因子，在机体对低氧浓度或缺氧应答中至关重要。武汉华美生物提供用于hif-1信号通路研究的蛋白、抗体、试剂盒 … Web10 de out. de 2024 · 细胞信号通路详解之HIF1α通路. 2024-10-10 22:30. 动物细胞中，对氧气的感知和反应是一个非常重要的过程，在包括癌症、心血管疾病和中风在内的多种疾病 … Web8 de jun. de 2013 · 分析测试百科 相关疾病：阿尔茨海默病各位GGJJ们，本人快被HIF-1a逼疯了！一直想把HIF-1a蛋白给做出来，试了很多办法，都没有成功！试过常规裂解液提蛋白，没结果。从论坛上看过用2*Loading buffer（不含溴酚蓝）裂解细胞，但发现个问题，就是：大培养皿，细胞数很多，加200ul 2*Loading buffer 后，裂解 ... dunipace juniors facebook