Higuchi and connors

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August undefined, 2024

WebSolubility profiles by Higuchi and Connors theory. So is the drug intrinsic solubility in cyclodextrin absence 76 . Source publication Alternative Technologies to Improve … WebTypes of phase-solubility diagrams according to Higuchi and Connors [11] showing how the total drug solubility changes with increasing CD concentration. A-type diagrams are …

Synthesis and characterization of NH2-(AEEA)n-amphotericin B

WebPhase-solubility studies Water solubility studies for both triterpenic acids were conducted by the Higuchi and Connors method [16] using a series of increasing concentrations of OGCD. In this purpose aqueous suspensions of oleanolic acid and ursolic acid, respectively, were prepared in the presence of OGCD in a concentration range of 1 to 300 ... WebJan 15, 2024 · Phase-solubility profiles and classification of drug/cyclodextrin complexes according to Higuchi and Connors (Higuchi and Connors, 1965). The phase solubility … great harvest bread co evanston

Eds.; Phase-Solubility Techniques, Wiley Interscience: (1965)

WebMay 1, 1999 · There are many methods for determination of stability constants of CyD complexes, using techniques such as solubility (Higuchi and Connors, 1965), … WebMay 11, 2024 · Cyclodextrins (CDs), a group of oligosaccharides formed by glucose units bound together in a ring, show a promising ability to form complexes with drug molecules … WebFeb 27, 2010 · According to Higuchi and Connors there can be five types of phase-solubility relationship (Fig. 1 ): A L -type where there is a linear relationship between substrate (drug) solubility and ligand (cyclodextrin) concentration and which is interpreted as formation of a complex with m :1 stoichiometry; A P -type, which represents positive deviation … great harvest bread co eugene

T. Higuchi and K. A. Connors, “Phase-Solubility Techniques,” In C.

Analysis of the phase solubility diagram of a …

Webevaluated by the methods described by Higuchi and Connors.20) Twenty mL of 0.007–0.252M CD aqueous solution in a glass beaker was placed in a 25 C water bath. Excess ALA was added to the CD solution and the mixture was homogenized at 2,000rpm with a T. K. ROBO MICS (Primix, Osaka, Japan). The suspension was ﬁltered WebMay 1, 1999 · There are many methods for determination of stability constants of CyD complexes, using techniques such as solubility ( Higuchi and Connors, 1965 ), potentiometry ( Miyaji et al., 1976 ), high-pressure liquid chromatography ( Uekama et al., 1978 ), and kinetic ( Bender and Komiyama, 1978) and spectroscopic ( Cramer et al., 1967, Thakkar et … fll water parkWebT. Higuchi, K. A. Connors, “Phase Solubility Techniques,” Advanced Analytical Chemistry of Instrumentation, Vol. 4, 1965, pp. 117-212. has been cited by the following article: TITLE: … fll wear for little girls

"WebPersonal papers of Takeru Higuchi, PP 359. University of Kansas. Kenneth Spencer Research Library. Higuchi and Connors, "Spectrophotometric Detection of the End Point in the Karl Fischer Titration of Water,", 1959, Box: 11, Folder: 110. Personal papers of Takeru Higuchi, PP 359. University of Kansas. Kenneth Spencer Research Library. " - Higuchi and connors

Higuchi and connors

Effect of β-cyclodextrins based nanosponges on the solubility of ...

WebJan 30, 2024 · According to Higuchi and Connors (1965), the linear host-guest correlation can be classified as linear diagram (A L) type because the straight line had a slope of less than 1 in each compound, i.e., 0.0074, 0.0202 and 0.0266 for curcumin, demethoxycurcumin, and bisdemethoxycurcumin, respectively. The result indicated that one mole of ... WebPhase solubility diagrams and their classification according to Higuchi and Connors. S0 is the intrinsic solubility of drugs in aqueous medium. Source publication +4 Cyclodextrins in Drug...

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WebJan 1, 2011 · T. Higuchi, K.A. Connors. Phase solubility techniques. Adv Anal Chem Instrum, 4 (1965), pp. 117-212. Google Scholar [18] L. Greenspan. Humidity Fixed Points of Binary Saturated Aqueous Solutions. J Res Nat Bur Stand, 81A (1) (1977), pp. 89-96. CrossRef Google Scholar [19]

http://www.sciepub.com/reference/10360 WebThis was explained by the solubilization theory of Higuchi and Connors. The solubility analysis of the ternary drug/competitor/CyD systems may be particularly useful for …

WebThis was explained by the solubilization theory of Higuchi and Connors. The solubility analysis of the ternary drug/competitor/CyD systems may be particularly useful for determination of the stability constant of a drug whose physicochemical and spectroscopic analyses are difficult, because they can be calculated by monitoring the solubility ... WebMar 22, 2024 · We also introduced the Higuchi and Connors method to analyze inclusion complex formed through solubilization and the pharmaceutical benefits that can be gained using CDs. In addition, the practical applications of CDs in nasal, ophthalmic, pulmonary, and rectal drug delivery are also described. CD applications for drug solubilization

WebHiguchi et. al, "Phase-Solubility Technique in Studying the Formation of Complex Salts of Triamterene,", 1964. Higuchi and Connors, "Phase-Solubility Techniques,", 1964. Higuchi …

WebIn vitro transdermal permeation behavior of isosorbide dinitrate in the absence and presence of 2-hydroxypropyl-β-cyclodextrin: solutions and suspensions. Interactions of a vasodilator, isosorbide dinitrate (ISDN), with the parent α-, β- and γ-cyclodextrins (α-, β- and γ-CDs) and 2-hydroxypropyl-α- and -β- and γ-CDs (HP-α- and -β ... great harvest bread co eau claire wisWebT K Higuchi, A Connors 31 Dec 1964 - Vol. 4, pp 212-217 About: The article was published on 1965-01-01 and is currently open access. It has received 2363 citation (s) till now. The … great harvest bread co evansville inWebJan 15, 2024 · Natural CDs and their derivatives are used as enabling pharmaceutical excipients that enhance aqueous solubility of poorly soluble drugs, increase drug permeability through biological membranes and improve drug bioavailability. great harvest bread co fargoWebMar 28, 2014 · Solubility studies were performed according to the method reported by Higuchi and Connors and the phase solubility diagrams were plotted. The repaglinide-nanosponges complexes were prepared, lyophilized and the resulted inclusion complexes were characterized by FT-IR and NMR. great harvest bread co duluth mnWebMar 30, 2024 · The phase solubility study was carried out according to the method of Higuchi and Connors ( Higuchi, & Connors, 1965 ). Specifically, excessive APG (approximately 10 mg) was added to 5 mL of ethanol–water (30:70, v/v) solution containing different concentrations of OMT in the range of 5–300 mM. great harvest bread co eagle idWebT. Higuchi and K. A. Connors, “Phase-Solubility Techniques,” In: C. N. Reilly, Ed., Advances in Analytical Chemistry and Instrumentation, Wiley-Interscience, New York, Vol. 4, 1965, pp. 117-212. has been cited by the following article: TITLE: Ibuprofen-Maltodextrin Interaction: Study of Enantiomeric Recognition and Complex Characterization great harvest bread co fort worthWebFeb 27, 2010 · According to Higuchi and Connors there can be five types of phase-solubility relationship (Fig. 1): A L-type where there is a linear relationship between substrate (drug) … fll weather airport