WebmiRDB is an online database for miRNA target prediction and functional annotations. All the targets in miRDB were predicted by a bioinformatics tool, MirTarget, which was developed by analyzing thousands of miRNA-target interactions from high-throughput sequencing experiments. Common features associated with miRNA binding and target ... WebDec 30, 2015 · By TargetScan analysis, we predicted FXN was the target gene of miRNA-145 and miRNA-182. Through real-time PCR analysis of clinical samples and experiments in cell lines, we confirmed that miRNA-145 but not miRNA-182 directly binds to the 3′ UTR region of FXN and negatively regulates its expression. We further found that through targeting FXN ...
Potential Critical Gene in Acute Myocardial Infarction IJGM
WebMay 25, 2024 · TargetScan analysis predicted sphingosine 1-phosphate receptor 1 (SIPR1) as a potential target for miR-181b-5p. CAGE showed binding to the promoter sequences of S1PR1. The downregulation or inhibition of S1PR1 led to decreased autophagic flux but enhanced the sensitivity to anticancer drugs in AGS R cells. This study presents a novel … WebTargetScan for iOS: Requires iPhone or iPad: €19.99: TargetScan for Android: Requires Android phone or tablet: €19.99: ... PC Software for group analysis. Just a few years ago a … bankentarifvertrag 2022 luxemburg
MicroRNA-144 inhibits cell proliferation, migration and invasion in ...
WebTargetScan analysis, real-time PCR, and a luciferase reporter assay were used to demonstrate the downstream target of miR-34a in OC cells. HDAC1 expression levels … WebFor actual analysis, it is necessary to integrate comprehensive analysis data on miRNAs and mRNAs and data on bioinformatic prediction of target genes to consider by narrowing down their relationship logically and efficiently. … bankentax