WebSep 1, 2016 · We found that house dust mite (HDM) extract induced TSLP production by nasal epithelial cells, suggesting that TSLP may be involved in development of HDM-induced allergic rhinitis (AR). To investigate that possibility in greater detail, wild-type and TSLP receptor-deficient (TSLPR −/− ) mice on the C57BL/6J background were repeatedly … WebJun 24, 2024 · Thymic stromal lymphopoietin (TSLP) was initially demonstrated to be critical in regulating inflammatory responses among various allergic disorders (such as …

Interleukin-37b Suppressed ILC2s in Children with Allergic Rhinitis

WebOct 1, 2015 · Although the involvement of TSLP in allergic rhinitis (AR) is suggested, the exact role of TSLP in AR is poorly understood. Furthermore, the relative contribution of … WebOct 23, 2014 · Since it was cloned in 1994, there has been accumulating evidence that TSLP is crucial for the maturation of antigen presenting cells and hematopoietic cells. TSLP genetic variants and its dysregulated expression have been linked to atopic diseases such as atopic dermatitis, asthma, allergic rhinitis and eosinophilic esophagitis. hangzhou chinese

Synergistic relationship between TSLP and IL‐33/ST2 signaling …

WebPollen, an ubiquitous allergen, is the trigger of seasonal rhinitis, conjunctivitis, and asthma, as well as an exacerbating factor of atopic dermatitis. However, the underlying mechanism by which pollen induces thymic stromal lymphopoietin (TSLP)-triggered allergic inflammation through epithelial innate immunity is largely unknown. WebDec 16, 2009 · A Role for TSLP in Gut Homeostasis. Although allergic reactions to normally innocuous antigens can result in damaging inflammation, Th2 immune responses are thought to have developed partially in ... WebJan 18, 2011 · Allergic rhinitis (AR) affects up to 80% of children with asthma and increases asthma severity. Thymic stromal lymphopoietin (TSLP) is a key mediator of allergic … hangzhou city brain